Can euploid embryos be identified in a non-invasive manner by measuring the concentration of specific metabolomic biomarkers in spent culture media?

As not all euploid embryos implant, is it possible to identify non-implanting euploid blastocysts from their spent media metabolomics profile?

Are there metabolites in spent media that can act as biomarkers to predict embryo implantation?

The aim of this study was to develop a novel non-invasive technique for embryo selection. This was performed by identification of metabolomics biomarkers of euploidy and aneuploidy in spent culture media after embryo culture.

The aim of the study was to develop an automated denudation device, supervised by a computer vision algorithm, that could reduce shear stress while efficiently removing cumulus cells to allow vitrification and ICSI and for subsequent NI-PGT or metabolomics analysis.

Can euploid embryos be identified in a non-invasive manner by measuring the concentration of specific metabolomic biomarkers in spent culture media?

Are there metabolites in the spent media that can act as biomarkers to predict embryo implantation?

As not all euploid embryos implant, is it possible to identify non-implanting euploid blastocysts from their spent media metabolomics profile?

The purpose of this study is to develop a microfluidic device to automate the critical process of vitrification and thawing procedures, providing standardization, minimizing inter and intra-center variability, and reducing hands-on time.